If you have been following like I have throughout all the rosacea support groups the confusion and frustration of diagnosing rosacea or what skin condition a sufferer has developed, you will notice that the list of subtypes, variants and other skin conditions keeps growing and growing. Time and again rosaceans report that they may have simultaneously another skin condition or that what was originally diagnosed as rosacea actually turns out later diagnosed as something else. I have been keeping a list of the skin conditions that keep coming up that mimic rosacea and/or require a differential diagnosis from a physician and the list currently is forty skin conditions or diseases. If you know of another one I may have missed I would appreciate knowing about it and the source.
The NRS has tried to help resolve some of this confusion by classifying rosacea into four subtypes and one variant. There are also sources that list a total of five other variants, making a total of nine (I found six more, so the total makes 15). Of these one source lists one skin condition that is a 'secondary feature of rosacea.'
Here are the subtypes of rosacea:
(1) Erythematotelangiectatic (ETR)
(characterized by persistent redness)
(2) Papulopustular
(characterized by persistent redness with bumps [papules] and pimples [pustules])
(3) Phymatous
(4) Ocular
Dr. Nase has proposed a fifth subtype,
(5) Neuropathic Rosacea [source] [another source]
One report sites even another phenotype distinct from the four subtypes:
Glandular Rosacea
Variants of Rosacea
The NRS only recognizes one variant, Granulomatous Rosacea. However, most medical literature discusses several other rosacea variants and there is no universal agreement of what constitutes a rosacea variant.
1. Granulomatous Rosacea
2. Rosacea Fulminans (pyoderma faciale or rosacea conglobata)
3. Steroid-induced acneiform eruption
4. Perioral dermatitis
5. Persistent edema of rosacea
6. Gram-negative Rosacea
7. Halogen Rosacea
8. Rosacea Conglobata
9. Rosacea Inversa
10. Lymphedema (Morbihan's disease)
11. Gnatophyma
12. Metophyma (forehead)
13. Motophyma (one or both ears)
14. Blepharophyma (eyelids)
15. Otophyma (ears)
I have proposed another variant:
16. Demodectic Rosacea
You can click here for a a partial list of photos.
If that isn't enough, I have complied a list of skin conditions or diseases that mimic rosacea, requiring a differential diagnosis by a qualified physician and here is the list:
| 1 |
- |
Acne Adult |
| 2 |
|
Acne Drug-induced
|
| 3 |
|
Acne Conglobata
|
| 4 |
|
Acne Vulgaris
|
| 5 |
|
Alcoholism
|
| 6 |
|
Allergic contact dermatitis
|
| 7 |
|
Bromoderma
|
| 8 |
|
Carcinoid syndrome
|
| 9 |
|
Cutaneous Lupus (rare)
|
| 10 |
|
Dermatomyositis |
| 11 |
|
Dermatophyte infection
|
| 12 |
|
Discoid Lupus (rare) |
| 13 |
|
Eczema
|
| 14 |
|
Erythematosus
|
| 15 |
|
Erysipelas
|
| 16 |
|
Folliculitis
|
| 17 |
|
Frostbite
|
| 18 |
|
Gram-negative folliculitis |
| 19 |
|
HIV
|
| 20 |
|
Lododerma
|
| 21 |
|
Keratosis Pilaris Rubra Faceii
|
| 22 |
|
Keratosis Pilaris Atrophans
|
| 23 |
|
Leukemia
|
| 24 |
|
Lupus chronic
|
| 25 |
|
Lupus Erythematosus, Acute
|
| 26 |
|
Lupus SLE,
|
| 27 |
|
Lupus Subacute
|
| 28 |
|
Lupus Subcutaneous |
| 29 |
|
Lupus vulgaris
|
| 30 |
|
Lymphoma
|
| 31 |
|
Mixed connective tissue disease |
| 32 |
|
Otophyma (rare) |
| 33 |
|
Pellagra |
| 34 |
|
Perioral Dermatitis |
| 35 |
|
Photodermatitis
|
| 36 |
|
Photosensitivity Drug-induced
|
| 37 |
|
Photosensitive eruption |
| 38 |
|
Pityrosporum Folliculitis
|
| 39 |
|
Polycythemia vera |
| 40 |
|
Polymorphous light eruption
|
| 41 |
|
Rheumetoid Arthritis
|
| 42 |
|
Sarcoidosis
|
| 43 |
|
Scleroderma
|
| 44 |
|
Seborrheic Dermatitis (commonly misdiagnosed)
|
| 45 |
|
Systemic Mastocytosis |
| 46 |
|
Sweet's syndrome (acute febrile neutrophilic dermatosis)
|
| 47 |
|
Sjrogen's Rynaunds disease
|
Another report says, "In 2004 in an article appearing in the Journal of the American Academy of Dermatology, Crawford et al. proposed the concept of glandular rosacea to describe another phenotype distinct from the four subtypes introduced by the expert committee. Glandular rosacea occurs predominantly in males who characteristically have oily skin, large pores, a tendency to rhinophyma, and inflammatory lesions, including papules, pustules and nodulocystic lesions, that extend onto the lateral cheeks and neck." source This same report says, "Debate also continues over whether rosacea conglobata and rosacea fulminans are variants of acne vulgaris or rosacea."
As you can see the mystery and confusion of rosacea only adds to the frustration and we need more research. I have formed a tax exempt non profit for rosacea that has been approved as a 501 (c) (3) organization that allows rosaceans a say into what research should be undertaken that may clear up some of this confusion. For more information
go to http://www.irosacea.org
Jason's anecdotal report
Kari's report of misdiagnosis with excema! |